Trauma can affect the brain in ways that creates lasting changes. The most impacted locations for this to occur are the hippocampus, the amygdala, and the prefrontal cortex. Stressors affecting the brain can lead to such diagnoses as Posttraumatic Stress Disorder. (Bremner, 2006). This type trauma can be a root cause of depression, substance abuse, disassociation, and potentially long term health problems. Stress can lead to poor sleep, hyperawareness, intrusive thoughts, and nightmares. These symptoms can lead to changes in memory, concentration and changes in the structure of the brain. (Bremner, 2006). Alterations of our memory functions due to stress can affect the hippocampus, the amygdala, and the prefrontal cortex, directly involved with managing our memories and memory creation.
References:
Bremner, J. D. (2006). Traumatic stress: Effects on the brain. Dialogues in clinical neuroscience. https://pmc.ncbi.nlm.nih.gov/articles/PMC3181836/

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